Chem-bla-ics
This blog deals with chemblaics in the broader sense. Chemblaics (pronounced chem-bla-ics) is the science that uses computers to address and possibly solve problems in the area of chemistry, biochemistry and related fields.
http://chem-bla-ics.blogspot.com/

ChemBark
ChemBark is a blog about chemistry, but not as technical as other blogs
http://blog.chembark.com

Cheminfo - chemistry blog
This blog is an online community where everybody is invited to join discussion of problems in the chemistry field. If you want news, opinions and discussion about the chemistry, it's all here.
http://www.allcheminfo.com/

Chemistry World blog
This blog provides a forum for news, opinions and discussion about the chemical sciences.
http://prospect.rsc.org/blogs/cw/

Depth-First - Walking the Web of Chemical Informatics
Depth-First covers cheminformatics from the perspective of a synthetic organic chemist turned software developer. Topics covered include cheminformatics Web development, object-oriented programming, Open Source software for cheminformatics, Open Access, and user interface design.
http://depth-first.com

Heterocyclic Chemistry
This blog deals with the syntheses and the functionalizations of heterocyclic rings (mainly 5 and 6 membered rings) by either unusual way, or with scalable procedures and in a straightforward manner.
http://hetchem.blogspot.com/

Mass Spectrometry Blog
A web log of mass spectrometry web sites, discussion groups, mailing lists and other links and items of interest to the mass spectrometry community.
http://msblog.kermitmurray.com

Molecule of the Day
This site is by a chemist who enjoys rambling about the relationship between chemistry and real life to non-chemists.
http://scienceblogs.com/moleculeoftheday/

Org Prep Daily
It is a blog with synthetic procedures. From the way it is written, any competent organic chemist can tell that the information is self-consistent and of high quality, with enough information to repeat the experiment and confirm that it worked.
http://orgprepdaily.wordpress.com/

The Sceptical Chymist
The Sceptical Chymist is a blog by the editors of Nature and the Research journals - and a forum for our readers, authors and the entire chemical community. We'll discuss what's new and exciting in chemistry and chemical biology, be it in our journals or elsewhere.
http://blogs.nature.com/thescepticalchymist/

TotallySynthetic
An impressive blog for natural product synthesis by Paul Docherty, a Ph. D student at Clare College, Cambridge. This blog has regular comments on synthesis papers (ca. 1 per day). There are between 10-20 useful comments on each from the blogosphere. Every month there is a vote on the best synthesis.
http://totallysynthetic.com/blog/

Triple Point: A Chemistry Blog
Triple Point is the English version of Ponto Triplo: a Portuguese chemistry blog with links to outstanding chemistry sites, news and events.
http://www.pontotriplo.org/triplepoint/

Useful Chemistry
The UsefulChem project is an initiative to carry out open source science based on current problems likely to have chemical solutions in the immediate future. This includes open discussion of strategies and objectives.
http://usefulchem.blogspot.com